个人简述:

任玉杰博士/教授，以第一作者或通讯作者在J.Org.Chem.,GreenChem.，EuropeanJournalofMedicinalChemistry，RSCAdvanced等国内外学术刊物上发表研究论文60余篇，申请（或授权）中国发明专利20余项。先后承担国家自然科学基金、上海市科委、上海市教委和企业委托开发等多个研究项目。

科研工作:

近2年代表性研究论文：1.Mei-LinLi,Yu-JieRen*,Ming-HuiDong,Wei-XinRen.Design,synthesisandstructuralexplorationofnovelfluorinateddabigatranderivativesasdirectthrombininhibitors.EuropeanJournalofMedicinalChemistry,2015,96,122-1382.Chun-LeiLi,Ming-HuiDong,Yu-JieRen*,Li-HuaLi.Design,synthesis,biologicalevaluationandmoleculardockingofnoveldabigatranderivativesaspotentialthrombininhibitors.RSCAdvances,2015,5,23737-237483.MinghuiDong,YujieRen*.Molecularmodelingstudiesofdihydro-alkyloxybenzyl-oxopyrimidines(DABOs)asnon-nucleosideinhibitorsofHIV-1reversetranscriptaseusing3DQSAR,TopomerCoMFAandmoleculardocking.RSCAdv,2015,5,13754–137614.Ming-HuiDong,Hai-FengChen,Yu-JieRen*,Fang-MingShao,Molecularmodeling,synthesisandbiologicalevaluationofdabigatrananaloguesasthrombininhibitors.Bioorganic&MedicinalChemistry,2016,24,73-845.MinghuiDong,YujieRen*,XiaodongGao.Identificationoftriazolo[4,5-b]pyrazinederivativesashepatocytegrowthfactorreceptorinhibitorsthroughstructure–activityrelationshipsandmoleculardockingsimulations.Bioorganic&MedicinalChemistryLetters,2015,25,4118-41266.Chengxu,YujieRen*.Molecularmodelingstudiesof[6,6,5]TricyclicFusedOxazolidinonesasFXainhibitorsusing3D-QSAR,TopomerCoMFA,moleculardockingandmoleculardynamicssimulations.Bioorganic&medicinalchemistryletters,2015,25(20),4522–45287.WeixinRen,YujieRen*,ShuaiWang,Design,synthesis,anticoagulantactivityevaluationandmoleculardockingstudiesofaclassofN-ethyldabigatranderivatives.EuropeanJournalofMedicinalChemistry.2016,120,148-1598.FeiJiang,JianlingSun,RenqiangYang,*ShanlinQiao,ZengjianAn,JianqingHuang,HaifangMao,GuieChenandYujieRen*,AFacileApproachtoPrepareMicroporousPolycarbazoleNetworkP-Tetra(4-(N-carbazolyl)phenyl)silanewithHighCO2StorageandSeparationProperties.NewJournalofChemistry,2016,40,4969-49739.FeiWang,Yu-JieRen*,Ming-HuiDong,Moleculardesign,synthesisandanticoagulantactivityevaluationoffluorinateddabigatrananalogues.Bioorganic&MedicinalChemistry,2016.24,2739–275310.XiaodongGao,LipingHanandYujieRen*,InSilicoExplorationof1,7-DiazacarbazoleAnalogsasCheckpointKinase1InhibitorsbyUsing3DQSAR,MolecularDockingStudy,andMolecularDynamicsSimulations.Molecules，2016,21(5),591doi:10.3390/molecules2105059111.Ming-HuiDong,Hai-FengChen,Yu-JieRen*,Fang-MingShao,Molecularmodeling,synthesisandbiologicalevaluationofdabigatrananaloguesasthrombininhibitors.Bioorganic&MedicinalChemistry,2016,24,73-84

教育背景:

东北师范大学获学士和硕士学位，大连理工大学获博士学位；大连化学物理研究所博士后，2003年12月-2004年12月：加拿大滑铁卢大学访问学者。