个人简述:

于政权简历2010/12-现在：中国农业大学副教授（国外优秀人才引进计划）03/2009-2010/12ResearchAssociate宾夕法尼亚大学细胞发育和皮肤病系Dr.SarahMillar实验室。2008-2009助理研究科学家(AssistantProjectScientist)加州大学,尔湾分校(Irvine)生化和医学系Dr.BogiAndersen实验室2004-2008.博士后(Postdoctoralresearcher),加州大学,尔湾分校(Irvine)生化和医学系Dr.BogiAndersen实验室09/2000-07/2003.Ph.D.中国农业大学生物学院09/1997-07/2000.M.S.生物学院,河北师范大学09/1993-07/1997.B.S.生物学院,河北师范大学研究领域：我们实验室主要研究兴趣是利用转基因和基因敲除小鼠揭示成体干细胞维持自我更新和多能性的分子调控机制。一方面，研究一些microRNA，RNA结合蛋白和转录因子在成体干细胞的功能。另一方面，利用体内干细胞追踪技术细胞寻找干细胞的标记基因，探索干细胞在正常发育和癌症发生过程中的作用。发表文章：1.ZhengquanYu,JMannik,ASoto,KLinandBAndersen,TheepidermaldifferentiationassociatedGrainyheadgeneGet1/Grhl3alsoregulatesurothelialdifferentiation.TheEMBOJournal200928(13):1890-903)2.ZhengquanYu,AmbicaBhandari,JaanaMannik,ThuPham,XiaomanXu,andBogiAndersen,Grainyhead-likefactorGet1/Grhl3regulatesformationoftheepidermalleadingedgeduringeyelidclosure.DevelopmentalBiology2008319(1):56-673.ZhengquanYu,KevinK.Lin,AmbicaBhandari,JoelA.Spencer,XiaomanXu,NingWang,ZhongxianLu,GordonN.Gill,DennisR.Roop,PhilipWertzandBogiAndersen.TheGrainyhead-likeEpithelialTransactivatorGet-1/Grhl3regulatesepidermalterminaldifferentiationandinteractsfunctionallywithLMO4.DevelopmentalBiology2006299(1):122-364.SunYing*,LiuDelong*,ZhengquanYu*,ZhangQian,BaiJuan,SunDaye;Anapoplasticmechanismforshorttermeffectsofrareearthelementsatlowerconcentrations.PlantCell&Environment200326(6):887-896(*theauthorscontributedequally)5.ZhengquanYu,MengQingyong,YuHongzhi,FanBaoliang,YuShuyang,FeiJing,WangLili,DaiYunpingandLiNingExpressionandbioactivityofrecombinanthumanlysozymeinthemilkoftransgenicmice.J.DairySci.200689:2911-29186.ZhengquanYu,LiYan,MengQingyong,ZhaoZhihui,LiWei,YuanJing,HuXiaoxiang,YanBingxue,FanBaoliang,YuShuyangandLiNing.ComparativeanalysisofthepigBACsequenceinvolvedinthemyostatingeneregulation.ScienceinChinaClifesciences2005vol.48No.2168-180.7.ZhengquanYu,FanBaoliang,DaiYunping,ZhengMing,NiuHuiling,WangMeili,WangLili,FeiJingandLiNing.Expressionofrecombinanthumanlysozymeinthemilkoftransgenicmice.ChineseScienceBulletin200348(21)2331-23358.ZhengquanYuandLining,Animalcloning:thepossiblemechanismsandresearchadvancement.Lettersinbiotechnology.200112(4):324-328(InChinese)9.NWang,KLin,ZLu,KLam,RNewton,XXu,ZhengquanYu,G.Gill,andBogiAndersen.TheLIM-onlyfactorLMO4regulatesexpressionoftheBMP7genethroughanHDAC2-dependentmechanism,andcontrolscellproliferationandapoptosisofmammaryepithelialcells.Oncogene,200726(44):6431-41.10.XXu,JMannik,EKudryavtseva,KLin,LFlanagan,JSpencer,ASoto,NWang,ZLu,ZhengquanYu,EMonukiandBAndersen,Co-factorsofLIMdomains(Clims/Ldb/Nli)regulatecornealhomeostasisandmaintenanceofhairfolliclestemcells.DevelopmentalBiology2007312(2):484-50011.MaLigeng,FanQingshu,ZhengquanYu,Zhouhualin,ZhangFusuoandSunDaye,DoesAluminuminhibitpollengerminationviaextracellularcalmodulin?PlantCellPhysiology,200041(3):372-37612.MengQY,ChenZQ,YuZQ,XieQFandLiN.Increasedbodyweightviainjectingmyogenicexpressiongrowthhormone-releasinghormone(GHRH)plasmidDNAintosheep.AnimBiotechnol.2004;15(2):175-92.

科研工作:

主持完成“863”子课题1项，正在主持“973”1项；转基因专项1项；自然科学基金面上项目1项；新世纪优秀人才；人才引进计划