科研工作:

主持的科研项目：国家自然科学基金青年基金项目（81400935）：Salsolinol合成酶的酶学性质及其在多巴胺能神经元变性死亡中的作用研究；国家博士后基金（71015999201201）：DNA股间交联导致的逆转录酶高表达与细胞癌变的关系；北京市博士后科学基金（71015999201203）：儿茶酚异喹啉类物质引起多巴胺能神经细胞毒性作用的机制研究。北京工业大学博士启动基金。主要代表论文：[1] Xuechai Chen, Yi Chen, Guosong Wu, Jianqing Lu, Javed Iqbal, Hong Qing, Yulin Deng *. Existence and characterization of salsolinol synthase in neuronal cells and rat brain, Neurochemical Journal, 2013, 7(3): 192-197. (SCI)[2] Abida Arshad #, Xuechai Chen #(co-first author), Zhenzhen Cong, Hong Qing, Yulin Deng *. TRPC1 protects dopaminergic SH-SY5Y cells from MPP+, salsolinol, and N-methyl-(R)- salsolinol induced cytotoxicity, Acta Biochim Biophys Sin, 2013, 11, 1-9. (SCI)[3]Xuechai Chen, Abida Arshad, Hong Qing, Rui Wang, Jianqing Lu, Yulin Deng *, Enzymatic condensation of dopamine and acetaldehyde: a salsolinol synthase from rat brain, Biologia, 2011, 66(6): 1183-1188. (SCI)[4]Xuechai Chen, Yulin Deng, Yi Lin, Daiwen Pang, Hong Qing, Feng Qu, Haiyan Xie *. Quantum dot-labeled aptamer bioprobes specifically targeting glioma cells. Nanotechnology, 2008, 19: 235105. (SCI)[5]谢海燕*，陈薛钗，邓玉林. 核酸适配体及其在化学领域的相关应用. 化学进展，2007, 19(6): 1026-1033.(SCI)[6]Xuechai Chen, Abida Arshad, Yi Chen, Shengping Dai, Yulin Deng *. Characterization of salsolinol synthase from rat brain, IEEE/ICME International Conference on Complex Medical Engineering-CME2011, 2011, 1-4.(EI)[7]Xuechai Chen, Abida Arshad, Xiaoyin Lin, Yi Chen, Jing Shen, Yongqian Zhang, Yulin Deng *. Preliminary purification of salsolinol synthase from rat brain, IEEE/ICME International Conference on Complex Medical Engineering-CME2011, 2011, 1-4. (EI)[8] Linna Zhao#, Xuechai Chen#, Yanyan Zhong, Qinxia Hou, Xuemei Ma, Minglian Wang, Rugang Zhong *. Nimustine induces DNA breaks and crosslinks in NIH/3T3 cells. International Journal of Bioscience, Biochemistry and Bioinfomatics, 2013, 3(3): 257-261. (EI)[9]陈薛钗, 赵琳娜, 张龙, 钟儒刚*. DNA 股间交联及与细胞癌变关系的研究进展. 化学通报, 2013, 76(8): 684- 688.[10]陈薛钗，王睿，Abida Arshad，邓玉林*. Pictet-Spenglerases及其相关生物学特性, 化学通报，2011, 74(3): 218- 224.[11]陈薛钗，王睿，毛键，丛珍珍，林汉斌，邓玉林*. Salsolinol合成酶的高效液相色谱-电化学活性检测方法研究，化学通报，2010, 10: 983- 942.[12]陈薛钗，邓玉林，林毅，庞代文，庆宏，谢海燕*. 量子点标记的aptamer对细胞目标蛋白的检测. 第五届全国化学生物学学术会议, 2007, 8: 50.

教育背景:

2011/06~2013/06，北京工业大学，生命科学与生物工程学院，博士后2007/09~2011/06，北京理工大学，生命学院，博士2005/09~2007/06，北京理工大学，生命学院，硕士2001/09~2005/06，温州师范学院，生物与环境科学系，学士