个人简述:

马季骅，二级教授，博士生导师       湖北省有突出贡献中青年专家。湖北省生物物理学会副理事长。武汉科技大学医学院生理学硕士点专家组组长。“European Biophysics Journal”、“Clinical and ExperimentalPharmacology and Physiology”、“Acta PharmacologicaSinica”和“生物物理学报”特邀审稿人。从事心脏电生理学研究。获得国家自然科学基金面上项目3项、湖北省自然科学基金1项、湖北省教育厅重大科研项目1项、与美国Gilead Sciences,Inc(雷诺嗪专利权的拥有者）国际合作项目4项，其它项目多项。发表研究论文66篇，其中SCI收录22篇，论文在Circulation等国际著名杂志上发表。获冶金工业部科技进步三等奖（第一完成人）1项，湖北省第十四届自然科学优秀学术论文特等奖1项。所指导的研究生，3篇论文分别获湖北省第十二、十三届自然科学优秀学术论文二等奖，1篇硕士论文获得湖北省优秀硕士学位论文奖。

科研工作:

项目名称及下达编号项目来源起讫时间科研经费(万元)本人承担任务： 托特罗定-一种心肌细胞持续性钠电流高效阻断剂的研究 (编号：81072637)国家自然科学基金项目2011.1—2013.1230.00主持心室肌细胞持续性钠电流与胞内钙离子之间的正反馈调节机制 （编号：30872637）国家自然科学基金项目2009.1—2011.1232.00主持稳心颗粒(国药准字Z10950026)药理、机理研究企、事业单位委托项目2014.1—2015.1230.00主持cAMP-蛋白激酶A系统对心室肌细胞瞬时钠电流和持续性钠电流之间互变现象的调制作用 (编号：30670764)国家自然科学基金项目2007.1—2009.1226.00主持Role of the amplitude of late sodium current in rabbit atrial myocytes: a comparison study with rabbit ventricular myocytes国际合作研究项目2011.5—2012.1240.00主持 近5年发表论文：(1) Luo AT#,Cao ZZ#, Xiang Y, ZhangS, Qian CP, Fu C,Zhang PH, Ma JH*, Ketamine Attenuatesthe Na+-Dependent Ca2+Overload in Rabbit Ventricular Myocytesin Vitro by Inhibiting Late Na+ andL-type Ca2+ Currents,Acta Pharmacol Sin, 2015, 36(11): 1327-1336 (2) Wu Y#,Wang L#, MaJ*, Song Y,Zhang P, Luo A, Fu C, Cao Z, Wang X, Shryock JC, Belardinelli L,Protein KinaseC and Ca2+-Calmodulin-Dependent Protein Kinase II Mediatethe Enlarged ReverseINCX Induced by Ouabain-Increased Late Sodium Currentin Rabbit VentricularMyocytes, Exp Physiol, 2015, 100(4): 399-409 (3) Luo A, Ma J*, Song Y, Qian C, WuY, Zhang P, Wang L, Fu C, Cao Z, Shryock JC, Larger Late Sodium CurrentDensityAs Well As Greater Sensitivities to ATX II and Ranolazine in Rabbit LeftAtrialthan Left Ventricular Myocytes, Am J Physiol Heart Circ Physiol, 2014,306(3):H455-H461 (4) Zhang P#,Xing J#, Luo A, Feng J,Liu Z, Gao C, Ma J*, Blockade of the Human Ether-a-go-go-RelatedGene PotassiumChannel by Ketamine, J Pharm Pharmacol, 2013, 65(9): 1321-1328 (5) Ma J#*, Luo A#, Wu L, Wan W,ZhangP, Ren Z, Zhang S, Qian C, Shryock JC, Belardinelli L, Calmodulin KinaseII andProtein Kinase C Mediate the Effect of Increased Intracellular CalciumtoAugment Late Sodium Current in Rabbit Ventricular Myocytes, Am J PhysiolCellPhysiol, 2012, 302(8): C1141-C1151 (6) Zhang S, Ma JH*, Zhang PH, LuoAT, Ren ZQ, KongLH, Sophocarpine Attenuates the Na+-Dependent Ca2+OverloadInduced by Anemonia Sulcata Toxin-Increased Late Sodium Current inRabbitVentricular Myocytes, J Cardiovasc Pharmacol, 2012, 60(4): 357-366  (7) Qian CP, Ma JH*, Zhang PH, LuoAT, Wang C, RenZQ, Kong LH, Zhang S, Wang XJ, Wu Y, Resveratrol Attenuates theNa+-dependentIntracellular Ca2+ Overload by Inhibiting H2O2-InducedIncrease inLate Sodium Current in Ventricular Myocytes, Plos One, 2012, 7(12):e51358, 1-10 (8) Ren Z, Ma J*, Zhang P, Luo A,Zhang S, Kong L,Qian C, The Effect of Ligustrazine on L-type Calcium Current,Calcium Transientand Contractility in Rabbit Ventricular Myocytes, J Ethnopharmacol,2012, 114(3):555-561页 (9) 孔令浩,马季骅*,张培华,罗岸涛,张硕,任志强,冯娟,陈玖玲，藜芦定增强反向Na+/Ca2+交换电流诱导家兔心室肌细胞内Ca2+超载和动作电位异常延长，生理学报，2012，64（4）：433 - 443页 (10) Wu L#*, MaJH#, Li H, Wang C,Grandi E, Zhang PH, Luo AT, BersDM, Shryock JC, Belardinelli L, Late SodiumCurrent Contributes to the ReverseRate-Dependent Effect of IKr Inhibition onVentricularRepolarization, Circulation, 2011, 123(16): 1713-1720