个人简述:

孙建伟，博士，教授。2010年毕业于中国科学院遗传与发育生物学研究所，之后进入美国佛罗里达Moffitt癌症研究中心进行博士后研究，2014年12月晋升为研究科学家，2015年4月被华南农业大学引进回国工作。孙建伟实验室主要以隐杆秀丽线虫（C.elegans）和癌细胞系及小鼠为研究对象，侧重于钙池操纵的钙流入及肌动蛋白集束蛋白Fasci调控失调在癌症发生、转移及扩散中的作用机制研究。

科研工作:

工作经历
2015.4--至今华南农业大学生命科学学院教授
2014.12-2015.4Moffitt癌症研究中心ResearchScientist
2010.12-2014.11Moffitt癌症研究中心Postdoctor
发表论文
1.ShengchenLin,ShuangLu,MentorMulaj,BinFang,TylerSKeeley,lixinWan,JihuiHao,MartinMuschol,JianweiSun*andShengyuYang*.monoubiquitinationinhibitsthebundlingactivityofFascin.JournalofBiologicalChemistry2016,Nov22.(*correspondenceauthor)
2.Fujian.Lu,Jianwei.Sun,Heping.ChengandShengyu.Yang,Fluorescence-basedmeasurementofstore-operatedCa2+entryincancercellsusingFluo-4andconfocallivecellimaging,MethodsMolBiol,（inpress）
3.JianweiSun,ShengchenLin,TylerSKeeley,ShengyuYang.DisseminatingMelanomaCellsSurfonCalciumWaves.Molecular&CellularOncology.
20152(4).pii:e1002714
4.YuefengSun,JianweiSun,PanidaLungchukiet,WaiseQuarni,ShengyuYang,XiaohongZhang,andWenlongBai.Fe65SuppressesBreastCancerCellMigrationandInvasionthroughTip60MediatedCortactinAcetylation.ScientificReport2015Jul135:11529.doi:10.1038/srep11529.
5.JianweiSun,FujianLu,HuifangHe,JunlingShen,JaneMessina,RahelMathew,DapengWang,AmodA.Sarnaik,Wei-ChiaoChang,MinjungKim,HepingCheng,andShengyuYang.STIM1-andOrai1-mediatedCa2+oscillationorchestratesinvadopodiumformationandmelanomainvasionJournalofCellBiology.2014Nov24,207(4):535-548.(HighlightedbyJCBeditor:http://jcb.rupress.org/content/early/2014/11/10/jcb.2074iti3)
6.Jaw-YuanWang*,JianweiSun*,Ming-YiiHuang,Ming-FengHou,Yu-ShiuanWang,YanSun,Yao-TingTsai,HuifangHe,ShengchenLin,ShengyuYang,andWei-ChiaoChang.STIM1OverexpressionpromotedColorectalCancerProgression,CellMotilityandCOX-2Expression.(*theseauthorscontributedequallytothiswork)Oncogene,2015Aug1334(33):4358-67
7.XiaoZhao,SongGao,HeRen,WeiSun,HuanZhang,ShengyuYang,JianweiSun,andJihuiHao.Hypoxiainduciblefactor-1promotespancreaticductaladenocarcinomainvasionandmetastasisthroughactin-bundlingproteinfascin.CancerResearch.2014May174(9):2455-64
8.JianweiSun,HuifangHe,SmithaPillai,YinXiong,SrideviChalla,LiyanXu,SrikumarChellappanandShengyuYang.GATA3TranscriptionFactorAbrogatesSmad4TranscriptionFactor-mediatedFascinOverexpression,InvadopodiumFormation,andBreastCancerCellInvasion.JournalofBiologicalChemistry.2013Dec27288(52):36971-82
9.JianweiSun,HuifangHe,YinXiong,ShuangLu,JunlingShen,AnnaCheng,Wei-ChiaoChang,Ming-FengHou,JohnathanM.Lancaster,MinjungKimandShengyuYang.FascinProteinIsCriticalforTransformingGrowthFactorProtein-inducedInvasionandFilopodiaFormationinSpindle-shapedTumorCells.JournalofBiologicalChemistry2011,286(45):38865–38875.
10.DidiChen,HuiXiao,KaiZhang,BinWang,ZhiyangGao,YouliJian,XiayingQi,JianweiSun,LongMiaoandChonglinYang.RetromerIsRequiredforApoptoticCellClearancebyPhagocyticReceptorRecycling.Science2010,327(5970):1261-4.
11.MeiYang*,JianweiSun*,XiaojuanSun,QinfangShen,ZhiyangGaoandChonglinYang.CaenorhabditiselegansProteinArginineMethyltransferasePRMT-5NegativelyRegulatesDNADamage-inducedApoptosis.PLoSGenet20095(6):e1000514.(*theseauthorscontributedequallytothiswork)
12.YouliJian,ZhiyangGao,JianweiSun,QinfangShen,FengFeng,YudongJingandChonglinYang.RNAaptamersinterferingwithnucleophosminoligomerizationinduceapoptosisincancercells.Oncogene(2009)28,4201–4211.
13.JianweiSun,TaoLiu,BaotaiGuo,DeminJin,ManliWeng,YanbinFeng,PuXu,DelinDuanandBinWang.DevelopmentofSSRPrimersfromESTSequencesandTheirApplicationinGermplasmIdentificationofPorphraLines(Rhodophyta).EuropeanJournalofPhycology2006,41(3):329-336.
14.JianweiSun,DeminJin,ChunjiangZhou,QingkaiYang,ManliWeng,DelinDuan,PuXu,JiahaiMaandBinWang.IdentificationofPorphyraLines(Rhodophyta)byAFLP-DNAFingerprintingandMolecularMarkers.PlantMolecularBiologyReporter2005,23(3):251-262.

教育背景:

博士博士研究生理学细胞生物学，发育生物学中国科学院遗传发育所全日制2006-2010
硕士硕士研究生农学作物遗传育种青岛农业大学全日制2003-2006
学士大学本科农学农学莱阳农学院全日制1999-2003