个人简述:

何伟，药剂学博士，副教授，破格博士生导师，江苏省高校“青蓝工程”优秀青年骨干教师。2012年毕业于复旦大学并获药剂学博士学位，研究方向：（1）大分子药物（基因、功能蛋白）的高效递送与免疫治疗；（2）纳米颗粒与药物自组装靶向递送系统。目前主持国家自然科学基金青年项目（NSFC 81402869）、江苏省青年基金（BK20140671）、教育部新教师基金（20130096120002），中央高校基本科研业务经费重点项目各1项（No.ZJ13151）；以第一或通讯作者身份发表SCI论文30余篇（最高因子9.03）。

科研工作:

近五年代表作：1.Xin, X. Pei, X. Yang, X. Lv, Y. Zhang, L. He W*, Yin L*. Rod-shaped active drug particles enable efficient and safe gene delivery. Advanced Science 2017, DOI: 10.1002/advs.201700324.2.He, W., Wang, Y., Lv, Y., Xiao, Q., Ye, L., Cai, B., Qin, C., Han, X., Cai, T., Yin, L., 2017. Denatured protein stabilized drug nanoparticles: tunable drug state and penetration across the intestinal barrier. Journal of Materials Chemistry B 5, 1081-1097.3.Zhang, L., Yang, X., Lv, Y., Xin, X., Qin, C., Han, X., Yang, L., He W*, Yin L*. 2017. Cytosolic co-delivery of miRNA-34a and docetaxel with core-shell nanocarriers via caveolae-mediated pathway for the treatment of metastatic breast cancer. Scientific Reports 7, 46186.4.He W#, Xiaofei Xin#, Yongji Li, Xiaopeng Han, Chao Qin,* and Lifang Yin*. Rod-Shaped Drug Particles for Cancer Therapy: The Importance of Particle Size and Participation of Caveolae Pathway, Part. Part. Syst. Charact. 2017, 34, 6, 201600371n/a.5.Jin Z, Lv Y, Cao H, Yao J, Zhou J, He, W*, Yin, L*. Core-shell nanocarriers with high paclitaxel loading for passive and active targeting.2016, Sci Rep. 2016 Jun 9 6:27559.6.Li, YJ Wu, ZN He, W* Qin, Chao Yao, Jing Zhou, Jianping Yin, L*. Globular protein-coated paclitaxel nanosuspensions: interaction mechanism, direct cytosolic delivery and significant improvement in pharmacokinetics. Molecular Pharmaceutics. 2015, 12.1485-15007.He, W. Yang, K. Yin, L*. Denatured globular protein and bile salt-coated nanoparticles for poorly water-soluble drugs: Penetration across the intestinal epithelial barrier into the circulation system and enhanced oral bioavailability. International Journal of Pharmaceutics 2015, 10.1016/j.ijpharm.2015.08.086.8.He, W. Jin, Z. Lv, Y. Cao, H. Yao, J. Zhou, J. Yin, L*. Shell-crosslinked hybrid nanoparticles for direct cytosolic delivery for tumor therapy. International Journal of Pharmaceutics 2015, 478, 762–772.9.Xu, CR, He, W*, Lv, Y., Qin, C. Lingjia Shen, Yin, L*.Self-assembled nanoparticles from hyaluronic acid-paclitaxel prodrugs for direct cytosolic delivery and enhanced antitumor activity. International Journal of Pharmaceutics2015, 493, 172-181.