个人简述:

华会明，女，博士，教授。1987年毕业于北京医科大学，获药学学士学位，1990年毕业于沈阳药科大学获药物化学硕士学位，1999年于同校获天然药物化学博士学位。2002-2003年在美国密西西比大学作访问学者。作为课题负责人主持了“十一五”新药创制重大专项1项、国家自然科学基金面上项目3项，以及省市级科研项目20余项。目前已在Org. Lett., J. Nat. Prod., Phytochemistry, Eur. J. Med. Chem., RSC Advances, J. Func. Foods, Tetrahedron等期刊发表SCI论文130余篇。申请专利19项，授权9项。

科研工作:

近年来发表代表性论文:1. Kai-Bo Wang, Da-Hong Li, Ping Hu, Wen-Jing Wang, Clement Lin, Jian Wang, Bin Lin, Jiao Bai, Yue-Hu Pei, Yong-Kui Jing, Zhan-Lin Li*, Danzhou Yang*, and Hui-Ming Hua*. A Series of β‑carboline alkaloids from the seeds of Peganum harmala show G-quadruplex interactions. Organic Letters, 2016, 18, 3398−3401 (IF = 6.732)2. Chun-Mei Sai, Da-Hong Li, Chun-Mei Xue, Kai-Bo Wang, Ping Hu,Yue-Hu Pei, Jiao Bai, Yong-Kui Jing, Zhan-Lin Li*, Hui-Ming Hua*. Two pairs of enantiomeric alkaloid dimers from Macleaya cordata. Organic Letters, 2015, 17, 4102-4105 (IF = 6.732)3. Kai-Bo Wang, Ying-Tong Di, Yu Bao, Chun-Mao Yuan, Gang Chen, Da-Hong Li, Jiao Bai, Hong-Ping He, Xiao-Jiang Hao, Yue-Hu Pei, Yong-Kui Jing, Zhan-Lin Li,* Hui-Ming Hua*. Peganumine A, a β-carboline dimer with a new octacyclic scaffold from Peganum harmala. Organic Letters, 2014, 16, 4028-4031. (IF = 6.732)4. Kangtao Tian#, Fanxing Xu#, Xiang Gao, Tong Han, Jia Li, Huaqi Pan*, Linghe Zang, Dahong Li*, Zhanlin Li, Takahiro Uchita, Ming Gao, Huiming Hua*. Nitric oxide-releasing derivatives of brefeldin A as potent and highly selective anticancer agents. European Journal of Medicinal Chemistry, 2017, 136, 131-143. (IF = 3.902)5. Tong Han, Jia Li, Jingjing Xue, He Li, Fanxing Xu*, Keguang Cheng, Dahong Li*, Zhanlin Li, Ming Gao, Huiming Hua*. Scutellarin derivatives as apoptosis inducers: Design, synthesis and biological evaluation. European Journal of Medicinal Chemistry, 2017, 135 270-281 (IF = 3.902)6. Kai-Bo Wang, Da-Hong Li, Yu Bao, Fei Cao, Wen-Jing Wang, Clement Lin, Wen Bin, Jiao Bai, Yue-Hu Pei, Yong-Kui Jing, Danzhou Yang, Zhan-Lin Li*, Hui-Ming Hua*. Structurally diverse alkaloids from the seeds of Peganum harmala. Journal of Natural Products, 2017, 80(2): 551-559. (IF = 3.662)7. Chun-Mei Sai, Da-Hong Li, Sheng-Ge Li, Tong Han, Yong-Zhi Guo, Yue-Hu Pei, Jiao Bai, Yong-Kui Jing, Zhan-Lin Li*, Hui-Ming Hua*. Racemic alkaloids from Macleaya cordata: Structural Elucidation, chiral resolution, and cytotoxic, antibacterial activities. RSC Advances, 2016, 6, 41173 – 41180 (IF = 3.289)8. Yan Bai, Dahong Li, Tingting Zhou, Ningbo Qin, Zhanlin Li, Zhiguo Yu*, Huiming Hua *. Coumarins from the roots of Angelica dahurica with antioxidant and antiproliferative activities. Journal of Functional Foods, 2016, 20, 453–462 (IF = 3.973)9. Ping Hu, Dahong Li , Kaibo Wang, Hao Wang, Zihou Wang, Zhanlin Li, Huiming Hua . New phenolic compounds from Vitex negundo var. heterophylla and their antioxidant and NO inhibitory activities. Journal of Functional Foods. 2015, 19: 174-181 (IF = 3.973)10 Zhi-Guo Liu, Zhan-Lin Li*, Jiao Bai, Da-Li Meng, Ning Li, Yue-Hu Pei, Feng Zhao*, Hui-Ming Hua*. Anti-inflamatory diterpenoids from the roots of Euphorbia ebracteolata. Journal of Natural Products, 2014, 77, 792-799 (IF = 3.662)