科研工作:

2013-2015北方寒地现代大农业区农业科技服务模式及技术集成与示范(2013BAD20B04)子课题-饲粮高/缺硒对猪糖/脂/硒代谢的影响，资助金额20万元，主持人。2013-2015国家支撑计划项目--功能性肽产品的创制与应用(2013BAD10B03)子课题-猪源抗菌肽设计改造、工程表达及应用，资助金额51.22万元，主持人。2013-2016国家自然科学基金项目--α-螺旋抗菌肽的分子改良、抑菌机理和真核表达的研究（31272453），资助金额80万元，主持人。2012-2014黑龙江省高等学校科技创新团队-饲用抗生素替代技术-饲用抗菌肽的研究与开发(2012TD003)资助金额100万元，主持人。2012-2016国家973课题--母体营养影响子代肉品质的代谢程序化机制（2012CB124703），子课题资助金额36.67万元，子课题主持人。2011-2015国家现代生猪产业技术体系--饲料营养价值评定与资源利用（CARS-36），资助金额350万元，岗位专家。2011-2013国家自然科学基金项目--β-防御素衍生物的分子设计及生物学活性的研究(31072046),资助金额35万元，主持人。2010-2012黑龙江省高教强省创新平台计划项目子项目-安全高效型奶牛专用精料补充料产业化生产关键技术，资助金额20万元，主持人。2010-2012黑龙江省教育厅重点项目--重组鸡β-防御素蛋白的制备及生物学活性研究(11551z003),资助金额3万元，主持人。2010-2012国家教育部项目--鸡防御素的克隆表达及产物对肉鸡影响的研究（20092325110009），资助金额6万元，主持人。近五年代表性著作、论文： 单安山主编.2013.《饲料资源开发与利用》.科学技术出版社.单安山主审（孙满吉编著）.2011.《反刍动物代谢疾病营养调控》.黑龙江科学技术出版社.单安山主审(徐良梅主编).2011.《渔用饲料分析与质量检测技术》.中国农业出版社.单安山主编（王安、马得莹合著）.2010.《肉品质的营养调控》.黑龙江科学技术出版社526.ZhiqiangJia,MinLiu,ZheQu,YuanyuanZhang,ShutongYin,andAnshanShan*.2014.ToxicEffectsofZearalenoneonOxidativeStress,InflammatoryCytokines,BiochemicalandPathologicalChangesinducedbythistoxinintheKidneyofPregnantRats.EnvironmentalToxicologyandPharmacology,37(2):580-591.525.Yin-FengLv,Jia-JunWang,HeGao,Ze-YunWang,NaDong,Qing-QuanMa,An-ShanShan*.2014.Mon61omolecularTryptophanProminentlyImpactingAntimicrobialPotencyofN-terminalActivityRegionfromtheAntimicrobialPeptidesPMAP-36.PlosOne.9(1):e86364.doi:10.1371/journal.pone.0086364.524.Jiu-liZhang&Zi-WeiZhang&An-ShanShan*&Shi-wenXu*.2014.EffectsofDietarySeleniumDeficiencyorExcessonGeneExpressionofSelenoproteinNinChickenMuscleTissues.BiolTraceElemRes,157:234–241.523.Q.Q.Ma,W.J.Jiao,Z.Y.Wang,C.X.Wu,A.S.Shan*,n,Y.B.Wang,J.M.Cai.2014.TissuespecificityandspeciessuperiorityofcathelicidingeneexpressioninChineseindigenousMinpigs.LivestockScience161：36–40522.XinZhu,NaDong,ZeyunWang,ZhiMa,LicongZhang,QingquanMa,AnshanShan*.2014.Designofimperfectlyamphipathicα-helicalantimicrobialpeptideswithenhancedcellselectivityandpotentantibiofilmactivity.ActaBiomaterialia,10(1):254-267.520.Q.Q.MaandA.S.Shan*.2013.NovelantimicrobialpeptidesrichinVal/Argresiduesandthebiologicalactivitiesinvitroandinvivo.AminoAcids.45(3):581.519.N.Dong,X.Zhu,Y.F.Lv,Q.Q.Ma,andA.S.Shan*.2013.Biochemicalpropertiesandmolecularmechanismsofantibacterialactionsofcarboxy-terminalRWL-taggedantimicrobialpeptidesAminoAcids.45(3):594.518.X.ZhuandA.S.Shan*.2013.ImportanceoftryptophanalongthenonpolarhelixfaceofanantimicrobialamphipathicpeptideforimprovingkillingefficacyagainstPseudomonasaeruginosa.AminoAcids.45(3):602.517.HuixinBai,QifangChang,BaomingShi,AnshanShan*.2013.Effectsoffulvicacidongrowthperformanceandmeatqualityingrowing-finishingpigs.LivestockScience,158(1-3):118-123.516.QiushiChen,HaoZhang,YanbinZheng,AnshanShan*,ZhongpengBi.2013.Effectsofenzymaticallyhydrolyzedbloodcellsongrowthperformanceandintestinalcharacteristicsofnewlyweanedpiglets.LivestockScience,157:514-519.515.F.Li,A.S.Shan*,J.W.Hu,Y.B.Zheng,L.M.Xu,andZ.H.Chen.2013.ChangestodailyfeedintakeduringthelayingperiodaltersembryonicMSTNandMYOGgeneexpressioningeneticallyfatandleanlinesofchickens.BritishPoultryScience.54（6）：728–737.514.L.S.Wang,Z.Shi,B.M.Shi,A.S.Shan*.2013.Effectsofdietarystevioside/rebaudiosideAonthegrowthperformanceanddiarrhearateofweanedpiglets.AnimalFeedScienceandTechnolog,187:104–109.513.WenJiang,LicongZhang,AnshanShan*.2013.TheeffectofvitaminEonlayingperformanceandeggqualityinlayinghensfedcorndrieddistillersgrainswithsolubles.PoultryScience,92(11):2956-2964..512.BinchaoSu，LingshengWang,HongWang,BaomingShi,AnshanShan*.2013.Conjugatedlinoleicacidandbetainpreventporkqualityissuesfromdietscontainingdistillers’driedgrainswithsolubles.CanadianJournalofAnimalScience.93(4):477-485.511.J.Du,S.Y.Cheng,W.X.Hou,B.M.Shi*,A.S.Shan*.2013.Effectivenessofmaifaniteinreducingthedetrimentaleffectsofcadmiumongrowthperformance,cadmiumresidues,haematologicalparameters,serumbiochemistryandactivitiesofantioxidantenzymesinpigs.BiologicalTraceElementResearch,155:49-55.510.Jian-ChaoFu,QiChen,JuanDu,Bao-MingShi*,An-ShanShan*.2013.EffectivenessofmaifaniteinreducingthedetrimentaleffectsofaflatoxinB1onhaematology,aflatoxinB1residues,andantioxidantenzymesactivitiesofweanlingpiglets.LivestockScience,157:218–224.509.Wan-NingHu,Wen-JingJiao,ZhiMa,NaDong,Qing-QuanMa,Chang-XuanShao,An-ShanShan*.2013.Theinfluenceofisoleucineandarginineonbiologicalactivityandpeptide-membraneinteractionsofantimicrobialpeptidesfromthebactericidaldomainofAvBD4.Protein&PeptideLetters,20(11):1189-99.508.YaoGu,An-ShanShan*,NaDong,Qing-QuanMa,Jian-PingLi,Bao-JingCheng.2013.AntitumoreffectoftheantimicrobialpeptideGLI13-8derivedfromdomainoftheavianβ-defensin-4.ActaBiochimicaetBiophysicaSinica,45:904–911.507.WeiFang,HeGao,YunheCao*,AnshanShan*.2013.CloningandexpressionofaxylanasegenefromAspergillusnigerIA-001inPichiapastoris.JournalofBasicMicrobiology,53:1-10.506.WenboLi,QifaChang,GangLiu,AnshanShan*andFengLi..2013.Effectofdistillersdriedgrainswithsolublesdietsupplementedwithrumen-protectedlysineandmethionineonmilkproductionandmilkaminoacidsinthelactatingcow.InternationalJournalofDairyTechnology,66:1-8.505.LianshengWang,ZhanShi,ZhiqiangJia,BinchaoSu,BaomingShi,AnshanShan*.2013.TheEffectsofDietarySupplementationwithChromiumPicolinatethroughoutGestationonProductivePerformance,CrConcentration,SerumParametersandColostrumCompositioninSows.BiologicalTraceElementResearch,154:55-61.504.JunshuYan,AnshanShan,HuanyuWang,DeyingMaandChangjiangYan.2013.InfluenceofSupercriticalCO2ExtractionofSchisandraChinensisonAntioxidantStatus,CarcassandMeatQualityofAABroilers.J.Poult.Sci.,50:219-227.503.YanbinZheng,QiushiChen,AnshanShan,HaoZhang.2013.Optimisationoftheenzymatichydrolysisofbloodcellswithaneutralprotease.JournalofBiomedicineandBiotechnology，2013,ArticleID2789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